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Lifespan: Why We Age-and Why We Don't Have To

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David A. Sinclair

11 Hours 56 Minutes

Simon & Schuster

September 2019

Audio Book Summary

Audio Bonus! Includes exclusive conversations with the authors!

A NEW YORK TIMES BESTSELLER

A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people.

It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan?

In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.”

This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger.

Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.

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Reviews

  • Doug H.

    This book is an interesting insight into the current research being performed in the field of aging and genetics. Dr. SInclair makes a compelling argument that aging is actually a disease rather than a "natural condition" that humanity must accept. There is quite a bit of science and medical/genetic research throughout the first half of the book, which personally, I found fascinating. He goes a bit off course more than halfway through the book when he begins to opine on what he feels are related topics such as global climate change, over-population, mankind's addiction to consumption of natural resources, and Earth's ecosystems inability to support all of the above. He also addresses the moral question of whether we should live longer or not. He makes no secret that he considers himself to be a globalist, humanist. While I may not agree with some of his opinions, he nonetheless is passionate about his work and is very conscientious about the impact that it may have in shaping the future of the world. Overall, it's an interesting read, but it could have been shortened greatly without the circumstantial diatribe on varying geopolitical issues such as energy consumption, use of natural resources, and political despotism against genetic research.

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  • Dennis L.

    David Sinclair added a lot to the quality of the book by taking great content and made it more enjoyable. As the narrator Thanks

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